Breaking News, Collaborations & Alliances

CytomX, AbbVie in Strategic Probody Drug Pact

To co-develop and commercialize Probody Drug Conjugates against CD71

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By: Kristin Brooks

Managing Editor, Contract Pharma

AbbVie and CytomX Therapeutics, Inc. have entered into a collaboration to co-develop and commercialize Probody Drug Conjugates against CD71, which is highly expressed in a number of solid and hematologic cancers and has molecular properties for efficient delivery of cytotoxic payloads to tumor cells.   Probody therapeutics are designed enhance the tumor-targeting features of an antibody and reduce drug activity in healthy tissues. CytomX has generated preclinical data that demonstrates that Pr...

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